MICROCAPSULATION – TECHNOLOGIES AND METHODS

Abstract

The article presents an overview of the application of technologies and methods of microcapsules in modern pharmaceuticals and the food industry. One of the most important tasks of healthcare is to provide the population with safe, effective, high-quality and affordable medicines. The analysis of the main rates of development of domestic medicines in the pharmaceutical market of Kazakhstan remains relevant. Microcapsulation is analyzed for physical, chemical, physico-chemical forms. With the help of microcapsulation, the following tasks can be solved: to reduce the reactivity of medicines, extend the shelf life of unstable and perishable medicines, reduce the toxicity of the substance, give the substance new physical properties, reduce volatility, change density, hide color, taste, smell. Microcapsules make it possible to ensure the long-term effect of medicines. Microcapsulation achieves: protection of unstable drugs from environmental influences (vitamins, antibiotics, enzymes, vaccines, serums, etc.); hiding the taste of bitter medicines; isolation of medicines in the desired part of the gastrointestinal tract (intestinalsoluble microcapsules); the question of obtaining high-quality capsules with properties and characteristics that dissolve in the desired environment, retain the therapeutic effect and at the same time meet the requirements of the consumer (ease of use, efficiency, reasonable cost) is still open.