Study of the effect of a seven -containing drug on the concentration of selenium in the organs and tissues of the lambs of the Romanov breed in the conditions of industrial complexes North-Western region

Abstract

Purpose: to study the effects of a selenic -containing drug on the concentration of selenium in blood serum, organs and tissues of lambs of the Romanov breed.Materials and methods. In the course of the study, 120 novels of the Romanov breed and 80 lambs obtained from the data of disemeters were used. The formation of control and experimental groups was carried out taking into account the principle of pair analysis. In experiments on assessing the effect of the drug, clinically healthy animals were used on the body. During the study, four groups of lambs were formed at the age of 30 days. The mothers of the first group during the period of suyagnity received the drug “e-sel” at the rate of 1 ml per 50 kg of live weight; The lambs of the first experimental group introduced the drug “E-sel” at the rate of 0.2 ml per 10 kg of live weight according to the instructions. The second group was a control - a physiological solution was administered in the same quantity as the drug with experimental animals; Feeding was carried out by the main diet. The studies were carried out in the period before the chopping (4 months of age) was carried out. Blood fence was carried out from the jugular vein. The concentration of selenium in blood serum lambs was determined by fluorimetrically with 2.3-diaminonaftalin. After the chopping, the lambs were slaughtered. The concentration of selenium in the organs and tissues of the lamb was examined by atomic-adsorption spectrometry.Results. It was established that the concentration of selenium in the lambs of the first experimental group increased, starting from the 60s from the moment of birth. At the same time, in the lambs of the first experimental group, the concentration increased 2.84 times by the 60th knocks compared to control, 4.08 times compared to control by the 90s from the moment of birth and 8.5 times by 120 -It day from the moment of birth. The concentration of selenium in the kidneys, liver and muscles (the broadest back muscle) of the first experimental group significantly exceeded the values of control. The maximum concentration was noted in the kidneys. No reliable changes were noted between the 1st and 2nd experimental groups in the concentrations of selenium in the kidneys and liver. The concentration of selenium in the liver of the experimental group was 2.94 times higher in comparison with control. In the kidneys, the concentration of selenium was 2.26 times higher for the experimental group in comparison with control. It is noted that an increase in the concentration of selenium in the muscles exceeded control indicators of 4.59, respectively.