Abstract
Atopic dermatitis (AD) is a chronic, relapsing, and remitting, inflammatory skin disease characterized by erythema, edema, xerosis, erosions/excoriations, oozing and crusting. It typically begins in childhood and often in infancy. The disease can wax and wane and for many patients it becomes less severe or even remits over time. Seasonal variation is common, with most patients experiencing a worsening of symptoms in the wintertime, particularly in Canada.
Reference15 articles.
1. Gooderham MJ, Bissonnette R, Grewal P, Lansang P, Papp KA, Hong CH. Approach to the assessment and management of adult patients with atopic dermatitis: a consensus document. Section II: tools for assessing the severity of atopic dermatitis. J Cutan Med Surg. 2018 Nov;22(1_suppl):10S-6S.
2. Asher MI, Rutter CE, Bissell K, Chiang CY, El Sony A, Ellwood E, Ellwood P, García-Marcos L, Marks GB, Morales E, Mortimer K. Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I Cross-sectional study. Lancet. 2021 Oct 30;398(10311):1569-80.
3. Weiss ST. Eat dirt—the hygiene hypothesis and allergic diseases. N Engl J Med. 2002 Sep 19;347(12):930-1.
4. Hill DA, Spergel JM. The atopic march: critical evidence and clinical relevance. Ann Allergy Asthma Immunol. 2018 Feb 1;120(2):131-7.
5. Kirchhof MG, Landells I, Lynde CW, Gooderham MJ, Hong CH. Approach to the assessment and management of adult patients with atopic dermatitis: a consensus document. Section I: pathophysiology of atopic dermatitis and implications for systemic therapy. J Cutan Med Surg. 2018 Nov;22(1_suppl):6S-9S.