Affiliation:
1. Samarth Institute of Pharmacy, Belhe, Maharashtra. India
Abstract
The main objective of the present study is to formulate the polyherbal antiaging cream and evaluation of various parameters of the cream. The evaluation parameters consist of phytochemical evaluation, physiological evaluation, stability studies, homogeneity, appearance, ph, etc. The polyherbal cream was formulated on basis of antioxidant activity of selected plant extracts. The cream was formulated by using natural herbal ingredients like Clitoria Ternatea (Butterfly pea), Mangifera indica (mango), and Annona squamosa (Custard Apple). Extraction of Mangifera indica and Annona Squamosa was carried out by cold maceration where Ethanol and distilled water used as solvent (Hydroalcoholic extraction). Extraction of Clitoria Ternatea was carried out by hot water extraction by using distilled water as a solvent. Phytochemical screening all the three extracts shows presence of flavonoids, tannins, alkaloids, and phenols. Formulated cream was evaluated by using different parameters such as pH, Appearance, Spreadability, Washability, Irritancy test, Stability Studies, etc. There is no evidence of phase separation and final formulation do not show rashes or redness, edema on skin. These study was suggest that different composition of all three extracts and base used in the cream are more stable and safe. It can be concluded from present study that herbal cream having an antioxidant activity without any side effect and can be used as a provision to barrier of skin and to avoid skin aging.
Reference21 articles.
1. Patil AP, Patil RV (2011) Clitoria Ternatea Linn: An overview Int. J. Pharm. Sci:3:20-23
2. G.M. Masud Parvez, Pharmacological activities of Mango (Mangifera Indica): A Review, January 2016
3. Reena Nair and Vijay Agrawal, A Review on the Nutritional Quality and Medicinal Value of Custard Apple-An Under Utilised Crop of Madhy Pradesh, India,Int.J.Curr.Microbiol.App.Sci (2017) 6(9): 1126-1132
4. Anila L, Vijayalakshmi.NR, Antioxidant action of flavonoids from Mangifera indica and Emblica officinalis in hypercholesterolemic rats. Food Chem., 2003; 83: 569–574.
5. Meran Keshawa Ediriweera, Kamani Hemamala Tennekoon, and Sameera Ranganath Samarakoon, A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds of Mangifera indica (Mango)