Affiliation:
1. New Montfort Institute of Pharmacy, Ashti, Wardha, Maharashtra
Abstract
The objective of present work is to formulate and evaluate herbal mouthwash and to evaluate its effectiveness against microbial load of oral cavity. The plant materials were collected and extracted for water soluble ingredients. Prepared mouthwash was further evaluated for its physicochemical properties and antimicrobial activity. The present mouthwash possesses a good antibacterial property. The results of stability study also confirm the effectiveness of preparation. Present mouthwash is a liquid preparation which normally contains antibacterial and antiseptic agents. Commercially available mouthwash formulations are often medicated and contain chemicals that may elicit adverse effects to the users. A mouthwash may be recommended for its efficacy in preventing dental caries other oral conditions due to its antimicrobial, anti-inflammatory properties
Reference29 articles.
1. Blot S. Antiseptic mouthwash, the nitrate-nitrite-nitric oxide pathway, and hospital mortality: a hypothesis generating review. Intensive Care Med. 2021;47(1):28-38. doi: 10.1007/s00134-020-06276-z, PMID 33067640. PMCID PMC7567004.
2. Vranić E, Lacević A, Mehmedagić A, Uzunović A. Formulation ingredients for toothpastes and mouthwashes. Bosnian J Basic Med Sci. 2004;4(4):51-8. doi: 10.17305/bjbms.2004.3362, PMID 15628997.
3. Li Y, Jiang X, Hao J, Zhang Y and Huang R: Tea polyphenols: application in the control of oral microorganism infectious diseases. Arch Oral Biol 2019; 102: 74-82.
4. Sedghi L, DiMassa V, Harrington A, Lynch SV and Kapila YL: The oral microbiome: Role of key organisms and complex networks in oral health and disease. Periodontol 2000. 2021; 87(1): 107-131,
5. Gamboa F, Estupinan M, Galindo A. Presence of Streptococcus mutans in saliva and its relationship with dental caries: Antimicrobial susceptibility of the isolates. Univ Sci, 2004; 9: 23-7.