Features of the Functional State of the Cardiovascular System and Microcirculation Processes in Patients with Neurocirculatory Asthenia and Fatigue

Abstract

Today, the urgent task of medicine is early diagnosis and differentiation of various functional disorders, which creates prerequisites for further adequate selection of drug and non-drug therapy. Based on the above, the aim of this study was to study the features of the functional state of the cardiovascular system, including microcirculatory processes, in patients with neurocirculatory asthenia and fatigue. Methods. The study included 51 patients with Fatigue and 52 patients with NCA. All patients were tested with physical activity on a Bicycle Ergometer, echocardiography, and the study of microcirculation using laser Doppler flowmetry. Results. Based on the conducted research, it was established that the tolerance to physical activity in the majority of patients with NCA and fatigue was reduced. However, in the group of patients with NCA, low tolerance was observed 2 times more often than in patients with Fatigue. In patients with NCA and overwork, the heterogeneity of microcirculatory disorders, manifested as hyperemic and spastic types of hemomicrocirculation, was established. At the same time, patients with NCA are 33% more likely to have a spastic type and 20% less likely to have a hyperemic type of microcirculation compared to patients with fatigue. Conclusion. The research has revealed the features of the functional state of the cardiovascular system and microcirculation processes in patients with neurocirculatory asthenia and fatigue. This makes it possible for early diagnosis and differentiation of the above functional diseases, which creates prerequisites for an adequate selection of drug and non-drug therapy.