Conventional and Diffusion MR Imaging Features of Ring-shaped Lateral Ventricular Nodules

Abstract

Objective: The aim of this study is to evaluate the conventional and diffusion MRI findings of ring-shaped lateral ventricular nodules (RSLVN) along with clinical features. Methods: MR images of all patients who underwent contrast-enhanced brain MRI between 2019 and 2023 were retrospectively evaluated. The number, shape, maximal diameter, and signal intensity of RSLVNs on T1-weighted (T1W), T2-weighted (T2W), fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted imaging (DWI), and contrast-enhancement status were evaluated. Apparent diffusion coefficient (ADC) values and normalized ADC ratios of nodules were also determined. If follow-up MRIs were performed, morphological changes of RSLVNs were evaluated. Results: RSLVN was observed in fifteen (0.51%) of 2920 patients. Multiple RSLVNs were observed in five patients and therefore a total of 23 RSLVNs were identified in fifteen patients. Nodules were located on the roof of the lateral ventricle in eight nodules (34.8%), in the frontal horn in twelve nodules (52.2%), and in the septum pellucidum in three. 6 of 23 RSLVNs (26.1%) were larger than 1 cm. All RSLVNs were isointense on T1W and T2W, while hyperintense on FLAIR. On DWI, 20 of 23 RSLVNs had isointense signal and the remaining 3 lesions were hyperintense. The mean ADC value and nADC ratio were 1.42 ± 0.29 x 10-3mm2 and 1.87 ± 0.31, respectively. Conclusion: RSLVNs may be more frequent than previously reported. Their uniform MRI appearance and typical localizations are distinctive, and they can reach relatively large sizes. Morphological stability during follow-up and the ADC values of these lesions suggest a possible benign nature.