Cellular composition research of serous pleural effusion fluids. Conceptual issues of preanalytics-Reference-Cited by-同舟云学术

Cellular composition research of serous pleural effusion fluids. Conceptual issues of preanalytics

Published:2021-03-13 Issue:2 Volume:66 Page:95-98
ISSN:2412-1320
Container-title:Russian Clinical Laboratory Diagnostics
language:
Short-container-title:Klin. lab. diagn.

Author:

Smetanina S. V.¹^ORCID,Uskova E. Y.U.¹^ORCID,Khusiyanova A. A.¹^ORCID,Danyaeva M. B.¹^ORCID,Korol’kova S. B.¹^ORCID,Slavnova E. N.²^ORCID,Voronova N. N.³^ORCID

Affiliation:

1. Nizhny Novgorod Regional Clinical Oncology Center

2. Moscow Research Oncological Institute named after P.A. Herzen - branch of the Federal State Budgetary Institution “National Medical Research Center of Radiology” of the Ministry of Health of the Russian Federation

3. FGAOU VO First MGMU named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)

Abstract

The purpose of this work was to show the effectiveness of the cytological method on a small number of observations, excluding all possible errors of the preanalytical stage. The paper presents several simple and easily reproducible algorithms for the cytological study of serous pleural effusions with small cellular content. On the example of 20 observations of the study of the cellular composition of serous exudates, a direct dependence of the research results on the preanalytical stage is shown. A complete study of effusion fluids in compliance with all stages of preanalytics and the use of modern methods of cytological diagnostics makes it possible to nullify the options for false-negative.

Publisher

EKOlab

Subject

Biochemistry (medical),Medical Laboratory Technology,General Medicine

Reference29 articles.

1. Incekara F.O., Tikici S.K., Nomenoglu H. Pleural Effusions. Insights in Chest Diseases. 2018;1:1-7. https://doi.org/10.21767/2577-0578.10040

2. Feller-Kopman D., Light R. Pleural Disease. The New England Journal of Medicine. 2018; 378:740-51. https://doi.org/10.1056/NEJMra1403503

3. Chuchalin A.G. Pulmonology [Pul’monologiya.] Moscow: GEOTAR-Media; 2016. (in Russian)

4. Walker S.P., Morley A.J., Stadon L., De Fonseka D., Arnold D.T., Medford A.R.L. et al. Nonmalignant Pleural Effusions: A Prospective Study of 356 Consecutive Unselected Patients. Chest. 2017; 151(5):1099-1105. https://doi.org/10.1016/j.chest.2016.12.014

5. Porcel J.M., Light, R.W. Pleural effusions. Dis Mon. 2013; 59: 29–57. doi.org/10.1016/j.disamonth.2012.11.002