Analysis of worldwide surgical outcomes in COVID-19-infected patients: a gynecological oncology perspective

Author:

Phelps David L12ORCID,Saso Srdjan12ORCID,Ghaem-Maghami Sadaf34ORCID

Affiliation:

1. Subspecialty Fellow, Gynaecological Oncology Surgery, Hammersmith and Queen Charlotte’s & Chelsea Hospital’s, Du Cane Road, London W12 0HS, United Kingdom

2. Honorary Clinical Lecturer, Department of Surgery & Cancer, Imperial College London, IRDB, Du Cane Road, London W12 0NN, United Kingdom

3. Professor of Gynaecological Oncology Surgery, Department of Surgery & Cancer, Imperial College London, IRDB, Du Cane Road, London W12 0NN, United Kingdom

4. Honorary Consultant Gynaecology Oncology Surgeon, Hammersmith and Queen Charlotte’s & Chelsea Hospital’s, Du Cane Road, London W12 0HS, United Kingdom

Abstract

Coronavirus Disease 2019 (COVID-19) guidance limits all but the most urgent surgery in the United Kingdom. We review the literature and our experience in gynecology to assess perioperative outcomes. PubMed was searched with (surg*[Title])AND(COVID[Title]), (surg*[Title])AND(2019-nCoV[Title]), and (surg*[Title])AND(SARS-CoV-2[Title]), and 67 COVID-19-positive surgical patients across ten hospitals in four countries are included. Median mortality was 33%. Cardiac and pulmonary co-morbidities associated with higher risk of COVID-19-positive postoperative death. Mortality was high in neurosurgery (80%) and the lowest in gynecological oncology surgery (none). This analysis provides an evidence base on which to consider surgical risk assessment for different specialties. Risk of perioperative death needs to be assessed in the context of patients’ co-morbidities and surgical specialty. An individualized approach toward surgical decision making is imperative.

Publisher

Future Science Ltd

Subject

Biotechnology

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