Mortality and glycemic control among patients with diabetes mellitus and uterine or ovarian cancer

Author:

Kusne Yael N1ORCID,Kosiorek Heidi E2ORCID,Buras Matthew R2ORCID,Coppola Kyle E3ORCID,Verona Patricia M4ORCID,Cook Curtiss B5ORCID,Karlin Nina J36ORCID

Affiliation:

1. Department of Internal Medicine, Mayo Clinic Hospital, Phoenix, AZ 85054, USA

2. Biostatistics, Mayo Clinic Hospital, Phoenix, AZ 85054, USA

3. Mayo Clinic Cancer Center, Mayo Clinic Hospital, Phoenix, AZ 85054, USA

4. Enterprise Technology Services, Mayo Clinic Hospital, Phoenix, AZ 85054, USA

5. Division of Endocrinology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA

6. Mayo Clinic, Scottsdale, Arizona, & Division of Hematology & Medical Oncology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA

Abstract

Aim: To evaluate associations between survival and glycemic control in age-matched patients with endometrial or ovarian cancer, with/without diabetes mellitus (DM). Patients & methods: Patients with newly diagnosed ovarian or endometrial cancer with and without DM were compared. Results: The study included 84 patients with ovarian cancer (28, DM); 96 with endometrial cancer (48 with, 48 without DM). DM patients did not have worse overall or progression-free survival than non-DM patients. Glycemic control was not associated with either cancer. Conclusion: There was no association between DM and survival for patients with uterine or ovarian cancer. In addition, there was no association between uterine and ovarian cancer and glycemic control. Additional studies to confirm these observations in larger populations are required.

Publisher

Future Science Ltd

Subject

Biotechnology

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