Does post-void residual urine volume affect potential recurrence risk for non-muscle invasive bladder cancer?

Author:

Al-Zubi Mohammad Talal1,Demour Saddam Al2,Al-Rawashdah Samer Fathi3,Carbone Antonio4,Pastore Antonio Luigi4,Abuhamad Mohannad2,Abuorouq Saleh1,Al-Azab Rami5,Bani-Hani Morad6,Al-Qudah Mohammad7,Elayan Basel8

Affiliation:

1. Department of Surgery, Division of Urology, School of Medicine, Yarmouk University, Irbid, 21110, Jordan

2. Department of Special Surgery, Division of Urology, School of Medicine, The University of Jordan, Amman, 11972, Jordan

3. Department of Special Surgery, Urology Unit, School of Medicine, Mutah University, Karak, 61710, Jordan

4. Department of Medico-Surgical Sciences & Biotechnologies, Unit of Urology, Faculty of Pharmacy & Medicine, Sapienza University of Rome, Latina, 04100, Italy

5. Department of Surgery & Urology, School of Medicine, Jordan University of Science & Technology, Irbid, 21110, Jordan

6. Department of Special Surgery, Division of Urology, School of Medicine, Hashemite University, Zarqa, 13110, Jordan

7. Faculty of medicine, University of Jordan, Amman, 11972, Jordan

8. Department of Special Surgery, Division of ENT, School of Medicine, The University of Jordan, Amman, 11972, Jordan

Abstract

Aim: Bladder cancer is the second most common urological malignancy after prostate cancer. Increase in the post-void residual (PVR) volume may result in an increase in the risk of cancer recurrence. Methods: Patient demographic data, tumor stage and grade, PVR volume and 2 years follow-up data for recurrence were obtained and evaluated. Results: One-hundred-and-nineteen patients were subdivided into three groups according to PVR urine volume. The increase of PVR volume was related to short recurrence-free survival (RFS) especially for patients with PVR volume of 60 ml or more. Conclusion: Low PVR volume in patients with non-muscle invasive bladder cancer may play a role in reducing cancer recurrence. However further research is needed in this field.

Publisher

Future Science Ltd

Subject

Biotechnology

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