Affiliation:
1. Department of Gastroenterology & Hepatology, Mohamed Tahar Maamouri University Hospital, Faculty of Medicine of Tunis, Tunis El Manar University, Nabeul, Tunisia
Abstract
Osteopetrosis is a rare genetic bone disorder characterized by a defect in osteoclasts recruitment and function. Its manifestations are numerous and they mainly include skeletal and dental deformities, cranial nerve entrapment and infections. Over time, osteoclastic expansion invades bone marrow leaving little space for hematopoietic cells. As a result, extramedullary hematopoiesis takes place in the reticular system mainly in the spleen and liver. In these patients, portal hypertension can occur as a result of extramedullary hematopoiesis associated splenomegaly. We are reporting in this article a rare case of spontaneous bacterial peritonitis associated with portal hypertension in a patient with osteopetrosis.
Cited by
1 articles.
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1. Malignant osteopetrosis of infancy: A case report;International Journal of Surgery Case Reports;2024-10