Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients-Reference-Cited by-同舟云学术

Impact of lifestyle modification on glycemic control and cognitive function among Type II diabetes mellitus patients

Published:2023-01 Issue:1 Volume:9 Page:
ISSN:2056-5623
Container-title:Future Science OA
language:en
Short-container-title:Future Science OA

Author:

Salama Iman I¹^ORCID,Sami Samia M²,Salama Somaia I¹,Abdel-Latif Ghada A¹^ORCID,Aboulghate Ahmed¹,Raslan Hala M³,Mohsen Amira¹,Rasmy Hanaa⁴^ORCID,Ibrahim Mona Hamed⁴,Ganem Mona MF³,Abdelmohsen Aida M¹,El-Etreby Lobna A¹,Ibrahim Nihad A¹,Fouad Walaa A¹,El-Deeb Sherif E¹

Affiliation:

1. Community Medicine Research Department, National Research Center, Cairo, 12622, Egypt

2. Child Health Department, National Research Center, Cairo, 12622, Egypt

3. Internal Medicine Department, National Research Center, Cairo, 12622, Egypt

4. Clinical & Chemical Pathology Department, Centre of Excellence, National Research Centre, Cairo, 12622, Egypt

Abstract

Aim: Assessing impact of lifestyle modification on Type 2 diabetes mellitus (T2DM) glycemic control and cognitive function. Subjects & methods: Prospective study was conducted on T2DM patients (92 patients as interventional group and 92 patients conventional therapy). Results: After 6 months, significant improvements of HbA1c, oxidant and antioxidant, lipid profile, and cognitive function among only the interventional group (p < 0.05). Using logistic analysis, conventional therapy, DM duration >10 years, lower education, HbA1c baseline >7 were significant predictive risks for uncontrolled DM (AOR 4.2, 2.9, 2.7 and 2.2, respectively). While, conventional therapy, baseline mild cognitive impairment (MCI) and females were significant risks for MCI (AOR 11.5, 10.8 and 4.8, respectively). Conclusion: Lifestyle modification is a very important for glycemic control and cognitive function.Clinical Trial Registration: NCT04891887 ( ClinicalTrials.gov )

Publisher

Future Science Ltd

Subject

Biotechnology

Link

https://www.future-science.com/doi/pdf/10.2144/fsoa-2022-0060

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