Author:
Fernández R. Nathalie ,Madrigal R. German ,Chavarría R. Marianela ,Matarrita B. Daniela ,Baltodano V. Eleaneth ,Carazo B. Gustavo ,Pacheco M. Jorge
Abstract
Microemulsions are two-phase oil-aqueous systems stabilized by a surfactant/cosurfactant system, formed from the spontaneous self-assembly of hydrophobic or hydrophilic parts of surfactant molecules, essential at the industrial level for their unique properties, improving processes and reducing costs. Their main uses in the pharmaceutical, cosmetic, and food industries are to improve the biopharmaceutical and pharmacokinetic properties of drugs, the skin penetration properties, and the stability and solubility of different ingredients. They are obtained by techniques such as phase inversion and phase titration. They are characterized by different techniques that allow obtaining information on the dynamic properties, droplet size, structural arrangement and orientation, molecular aggregation, and system interactions, which allow improving the formulations continuously. Due to their proven advantages and utilities, as well as their potential applications, it is essential to study these systems.
Publisher
European Open Science Publishing
Reference71 articles.
1. Talianu MT, Dinu-Pîrvu CE, Ghica MV, Anuţa V, Jinga V, Popa L. Foray into Concepts of Design and Evaluation of Microemulsions as a Modern Approach for Topical Applications in Acne Pathology. Nanomaterials. 2020 Nov 19;10(11):2292. doi: 10.3390/nano10112292.
2. Lee KL. Applications and Use of Microemulsions. 2010;6.
3. Salicio MM, Moreno MD. Colloids and interfaces. [Coloides e interfases]. 1ª ed. España: Universidad de Salamanca; 2005. 480 p.
4. Flanagan J, Singh H. Microemulsions: A Potential Delivery System for Bioactives in Food. Crit Rev Food Sci Nutr. 2006 Apr 1;46(3):221–37. doi: 10.1080/10408690590956710.
5. Galán JJ. Influence of temperature on the micellar properties of quaternary ammonium salts in aqueous solution. [Influencia de la temperatura en las propiedades micelares de sales cuaternarias de amonio en disolución acuosa]. Universidad de Santiago de Compostela; 2008.