Sebaceous Carcinoma of the Eyelid: A Case Report and Review of the Literature

Abstract

Palpebral sebaceous carcinoma (PSC) is a rare malignant disease. Despite the possibility of extraocular location, the ocular region is the most described site in the literature. This tumor is poorly known and can mimic various benign conditions, explaining the frequent diagnostic delays. We report a new observation of sebaceous carcinoma in a 59-year-old patient and a review of the literature. It mainly affects the elderly with a female predominance.  Its location in the upper eyelid remains the most common site, unlike our patient who presented with a lower eyelid disease. Surgery seems to be the treatment of choice for local sebaceous cell carcinoma, the role of radiotherapy is still to be clearly defined but the studies detailed in our paper have confirmed its effectiveness in inoperable patients or patients with advanced local disease, the use of chemotherapy during or before radiotherapy remains to be clarified.