Twin to Twin Transfusion Syndrome in Discordance Twins: Diagnostic and Management Approach

Abstract

Twin to twin tranfusion syndrome (TTTS) is a rare condition that affects the identical twin pregnancy or other multiples. TTTS occurs when there is an imbalance in blood flow between fetuses who share one placenta. This condition can cause one fetus to be dominant among other fetuses or is called discordant twins. The cause of discordant twins is still unclear. But one of the causes is Twin-to-Twin Tranfusion Syndrome. The incidence of discordant twin pregnancies is around 15-29% of total pregnancies. The chance of developing TTTS is estimated to be around 10-15% of monochorionic diamniotic. TTTS is diagnosed by ultrasonography with measuring the single deepest pocket (SDP). TTTS can be treated by fetoscopy laser ablation. The aim of this treatment is to close the connection of blood vessels. There are alternative treatments such as amnioreduction, selective fetal reduction, or termination of pregnancy.