Author:
K. K Kishore, ,R. Hiremath Rudramma,B. Gundakalle Mahadev,B. S Prasad,S. Skandan
Abstract
Renal calculi, one of the most common social problems caused by incorrect urine elimination. By the process of excretion of urine in excess quantity, Mutrala drugs help in the removal of renal stones through the urine or lessen their size. A novel decoction was prepared by ingredients having diuretic and lithotropic action. Mutrala kashaya was prepared by boiling coarse powder of Boerhavia diffusa Linn., Treibulus terrestris Linn., Bergenia ligulata Wall., Crateva nurvala buch Ham., Coriandrum sativum Linn., Vetivera zizanoids Linn., Benincasa hispida Thunb. and Vigna unguiculata Linn. Phyto-and physiochemical values of all drugs were under standard range of API. Total solids of Mutrala kashaya is 4.92 %, pH is 4.5, specific gravity is 1.04, refractive index is 1.349, viscosity is 0.00125 mm2 sec-1. HPTLC showed 16 Rf values. It shows presence of reducing sugars (1.5%), fats, and oils along with cardiac and saponin glycosides. Mutrala kashaya can be developed by using herbal drugs having diuretic and lithotrophic effects.
Publisher
Indian Drug Manufacturers' Association (IDMA)
Subject
Drug Discovery,Pharmaceutical Science,Pharmacology
Reference34 articles.
1. 1. Mishra L., Singh BB and Dagenais S.: Healthcare and disease management in Ayurveda. Altern. Ther. Health Med., 2001;7(2):44-50
2. 2. Bhat SD, Ashok BK etal Critical analysis of herbs acting on Mutravahasrotas. AYU, 2010 [cited 2020 Jan 14];31:167-9
3. 3. Malson G., New GLP-1 agonist claims price advantage http://www.pharmaceutical-journal.com/learning/learning-article/new-glp-1-agonist-claims-price-advantage/11122965.article 26 July 2020
4. Preventive fluid and dietary therapy for urolithiasis: An appraisal of strength, controversies and lacunae of current literature;Agarwal;Journal of the Urological Society of India,2011
5. 5. Ghalayini IF, Al-Ghazo MA, Harfeil MN. Prophylaxis and therapeutic effects of raspberry (Rubus idaeus) on renal stone formation in Balb/c mice. Int. braz j urol : off. j. Braz. Soc. Urol., 2011;37(2):259-66; discussion 67.