Author:
Singh Satvir, ,Bhandari Divya,Gupta Monika,Kaur Chamanpreet,Rani Anju,Devi Sunita
Abstract
Benzoic acid substituted imidazo[2,1-b][1,3,4]thiadiazoles were synthesized using appropriate reaction scheme. The synthesized derivatives were then purified and elucidated for their structure by measuring their melting points, infra-red spectra and proton NMR spectra. The progress of the reaction was determined by using thin layer chromatography technique. The antimicrobial potential of the synthesized derivatives was evaluated against S. aureus and E. coli. The zone of inhibition (mm) was measured. Reported derivatives showed good to moderate antibacterial activity
Publisher
Indian Drug Manufacturers' Association (IDMA)
Subject
Drug Discovery,Pharmaceutical Science,Pharmacology
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