Assessment of In Vivo Clinical Product Performance of a Weak Basic Drug by Integration of In Vitro Dissolution Tests and Physiologically Based Absorption Modeling-Reference-Cited by-同舟云学术

Assessment of In Vivo Clinical Product Performance of a Weak Basic Drug by Integration of In Vitro Dissolution Tests and Physiologically Based Absorption Modeling

Published:2015-07-01 Issue:6 Volume:17 Page:1395-1406
ISSN:1550-7416
Container-title:The AAPS Journal
language:en
Short-container-title:AAPS J

Author:

Ding Xuan,Gueorguieva Ivelina,Wesley James A.,Burns Lee J.,Coutant Carrie A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1208/s12248-015-9797-6.pdf

Reference43 articles.

1. Martinez MN, Amidon GL. A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals. J Clin Pharmacol. 2002;42(6):620–43.

2. Lennernäs H. Human intestinal permeability. J Pharm Sci. 1998;87(4):403–10.

3. Karlsson J, Ungell A-L, Grasjo J, Arturrson P. Paracellular drug transport across intestinal epithelia: influence of charge and induced water efflux. Eur J Pharm Sci. 1999;9(1):47–56.

4. Ayrton A, Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica. 2001;31(8-9):469–97.

5. Hou T, Wang J, Zhang W, Wang W, Xu X. Recent advances in computational prediction of drug absorption and permeability in drug discovery. Curr Med Chem. 2006;13(22):2653–67.

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Predictability of human exposure by human‐CYP3A4‐transgenic mouse models: A meta‐analysis;Clinical and Translational Science;2023-12

2. A Combined In-Vitro and GastroPlus® Modeling to Study the Effect of Intestinal Precipitation on Cinnarizine Plasma Profile in a Fasted State;AAPS PharmSciTech;2023-05-12

3. Best Practices for Integration of Dissolution Data into Physiologically Based Biopharmaceutics Models (PBBM): A Biopharmaceutics Modeling Scientist Perspective;AAPS PharmSciTech;2023-02-09

4. Approaches of formulation bridging in support of orally administered drug product development;International Journal of Pharmaceutics;2022-12

5. Current State and Challenges of Physiologically Based Biopharmaceutics Modeling (PBBM) in Oral Drug Product Development;Pharmaceutical Research;2022-09-08