Addressing the Challenges of Low Clearance in Drug Research
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmaceutical Science
Link
http://link.springer.com/content/pdf/10.1208/s12248-014-9691-7.pdf
Reference22 articles.
1. Roffey SJ, Obach RS, Gedge JI, Smith DA. What is the objective of the mass balance study? A retrospective analysis of data in animal and human excretion studies employing radiolabeled drugs. Drug Metab Rev. 2007;39(1):17–43.
2. Di L, Kerns EH, Ma XJ, Huang Y, Carter GT. Applications of high throughput microsomal stability assay in drug discovery. Comb Chem High Throughput Screen. 2008;11(6):469–76.
3. Hop CECA, Cole MJ, Davidson RE, Duignan DB, Federico J, Janiszewski JS, et al. High throughput ADME screening: practical considerations, impact on the portfolio and enabler of in silico ADME models. Curr Drug Metab. 2008;9(9):847–53.
4. Rudewicz PJ, Yue Q, Shin Y. High-throughput strategies for metabolite identification in drug discovery. High-Throughput Analysis in the Pharmaceutical Industry. 2009;141–54
5. Di L, Kerns EH, Carter GT. Drug-like property concepts in pharmaceutical design. Curr Pharm Des. 2009;15(19):2184–94.
Cited by 72 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion;Oral Bioavailability and Drug Delivery;2023-10-10
2. Use of Human Intestinal and Hepatic Tissue Fractions and Microbiome as Models in Assessment of Drug Metabolism and its Impact on Oral Bioavailability;Oral Bioavailability and Drug Delivery;2023-10-10
3. Peptide-based vaccine for cancer therapies;Frontiers in Immunology;2023-08-16
4. Recent advances in measurement of metabolic clearance, metabolite profile and reaction phenotyping of low clearance compounds;Expert Opinion on Drug Discovery;2023-08
5. HPLC methods for studying pharmacokinetics of tivozanib and in vitro metabolic interaction with dexamethasone in rat;Journal of Pharmaceutical and Biomedical Analysis;2023-08
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3