The Gender of Cell Lines Matters When Screening for Novel Anti-Cancer Drugs

Author:

Nunes Larissa M.,Robles-Escajeda Elisa,Santiago-Vazquez Yahaira,Ortega Nora M.,Lema Carolina,Muro Almendra,Almodovar Gladys,Das Umashankar,Das Swagatika,Dimmock Johnatan R.,Aguilera Renato J.,Varela-Ramirez Armando

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Reference9 articles.

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2. Schiebinger L. Gendered innovations: how gender analysis contributes to research. Created: 6/14/2013, Modified: 7/8/2013. Report of the Expert Group “Innovation through Gender” http://ec.europa.eu/research/science-society/document_library/pdf_06/gendered_innovations.pdf (accessed in April, 2014).

3. Zhang L, Li PP, Feng X, Barker JL, Smith SV, Rubinow DR. Sex-related differences in neuronal cell survival and signaling in rats. Neurosci Lett. 2003;337:65–8.

4. Deitch EA, Feketeova E, Lu Q, Zaets S, Berezina TL, Machiedo GW, et al. Resistance of the female, as opposed to the male, intestine to I/R-mediated injury is associated with increased resistance to gut-induced distant organ injury. Shock. 2008;29:78–83.

5. Penaloza C, Estevez B, Orlanski S, Sikorska M, Walker R, Smith C, et al. Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells. FASEB J. 2009;23:1869–79.

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