Semi-mechanistic Modeling of the Interaction Between the Central and Peripheral Effects in the Antinociceptive Response to Lumiracoxib in Rats-Reference-Cited by-同舟云学术

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Semi-mechanistic Modeling of the Interaction Between the Central and Peripheral Effects in the Antinociceptive Response to Lumiracoxib in Rats

Published:2012-09-12 Issue:4 Volume:14 Page:904-914
ISSN:1550-7416
Container-title:The AAPS Journal
language:en
Short-container-title:AAPS J

Author:

Vélez de Mendizábal Nieves,Vásquez-Bahena Dalia,Jiménez-Andrade Juan M.,Ortiz Mario I.,Castañeda-Hernández Gilberto,Trocóniz Iñaki F.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1208/s12248-012-9405-y.pdf

Reference29 articles.

1. García-Rodríguez LA, Hernández-Díaz S. The risk of upper gastrointestinal complications associated with nonsteroidal anti-inflammatory drugs, glucocorticoids, acetaminophen, and combinations of these agents. Arthritis Res. 2001;3:98–101.

2. Crofford LJ. COX-1 and COX-2 tissue expression: implications and predictions. J Rheumatol. 1997;49(Suppl):15–9.

3. Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A. 1999;96:7563–8.

4. Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem. 1990;265:16737–40.

5. Mysler E. Lumiracoxib (Prexige): a new selective COX-2 inhibitor. Int J Clin Pract. 2004;58:606–11.

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