Factors Influencing the Use and Interpretation of Animal Models in the Development of Parenteral Drug Delivery Systems

Author:

Martinez Marilyn N.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Reference109 articles.

1. Martinez M. Interspecies differences in physiology and pharmacology: extrapolating preclinical data to human populations. In: Rogge MC, Taft DR, editors. Preclinical Drug Development. 2nd ed. Boca Raton: Taylor and Francis Group; 2009. p. 35–70.

2. Kararli TT. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. Biopharm Drug Dispos. 1995;16(5):351–80.

3. de Zwart LL, Rompelberg CJM, Sips AJAM, Welink J, and van Engelen JGM. Anatomical and physiological differences between various species used in studies on the pharmacokinetics and toxicology of xenobiotics. A review of literature. RIVM report 623860 010: October 1999. http://www.rivm.nl/bibliotheek/rapporten/623860010.pdf . Accessed 1 Oct 2011.

4. Martignoni M, Groothuis GMM, de Kanter R. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition, and induction. Expert Opin Drug Metab Toxicol. 2006;2(6):875–94.

5. Martinez MN, Pedersoli WM, Ravis WR, Jackson JD, Cullison R. Feasibility of interspecies extrapolation in determining the bioequivalence of animal products intended for intramuscular administration. J Vet Pharmacol Ther. 2001;24(2):125–35.

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