Empirical versus mechanistic modelling: Comparison of an artificial neural network to a mechanistically based model for quantitative structure pharmacokinetic relationships of a homologous series of barbiturates-Reference-Cited by-同舟云学术

Empirical versus mechanistic modelling: Comparison of an artificial neural network to a mechanistically based model for quantitative structure pharmacokinetic relationships of a homologous series of barbiturates

Published:1999-12 Issue:4 Volume:1 Page:5-13
ISSN:1522-1059
Container-title:AAPS PharmSci
language:en
Short-container-title:AAPS PharmSci

Author:

Nestorov Ivan,Rowland Malcolm,Hadjitodorov S. T.,Petrov I.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1208/ps010417.pdf

Reference39 articles.

1. Thakur AK, Model mechanistic vs empirical. In: Rescigno A, Thakur AK, eds. New Trends in Pharmacokineties. New York: Plenum Press. 1991; 41–51.

2. Rescigno A, Beck JS (Comments: Thakur AK). The use and abuse of models. I Pharmacokinet Biopharm. 1987;15:327.

3. Veng-Pedersen P, Modi NB. Neural networks in pharmacodynamic modeling: is current modeling practice of complex kinetic systems at a dead end? J Pharmacokinet Biopharm. 1992;20:397–412.

4. Siegel RA. Commentary on “Neural networks in pharmacodynamic modeling: is current modeling practice of complex kinetic systems at a dead end?” J Pharmacokinet Biopharm. 1992;20:413–416.

5. Veng-Pedersen P. Response to Siegel's commentary. J Pharmacokinet Biopharm. 1992;20:417–418.

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