Experimental Aspects of Measuring the Vial Heat Transfer Coefficient in Pharmaceutical Freeze-Drying

Author:

Wegiel Lindsay A.,Ferris Steven J.,Nail Steven L.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics

Reference10 articles.

1. Philippidis A. The top 15 best-selling drugs of 2016. Genetic Engineering & Biotechnology News. 2017. http://www.genengnews.com/the-lists/the-top-15-best-selling-drugs-of-2016/77900868 . Accessed 05 Sep 2017.

2. Nail SL, Searles JA. Elements of quality by design in development and scale-up of freeze-dried parenterals. Biopharm Int. 2008;21(1)

3. Mockus LN, Paul TW, Pease NA, Harper NJ, Basu PK, Oslos EA, et al. Quality by design in formulation and process development for a freeze-dried, small molecule parenteral product: a case study. Pharm Dev Technol. 2011;16(6):549–76.

4. Pikal M. Use of laboratory data in freeze drying process design: heat and mass transfer coefficients and the computer simulation of freeze drying. PDA J Pharm Sci Technol. 1985;39(3):115–39.

5. Pikal M, Roy M, Shah S. Mass and heat transfer in vial freeze-drying of pharmaceuticals: role of the vial. J Pharm Sci. 1984;73(9):1224–37.

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