Influence of Plasdone™ S630 Ultra—an Improved Copovidone on the Processability and Oxidative Degradation of Quetiapine Fumarate Amorphous Solid Dispersions Prepared via Hot-Melt Extrusion Technique

Author:

Butreddy Arun,Sarabu Sandeep,Bandari Suresh,Batra Amol,Lawal Kamaru,Chen Nick Ningyi,Bi Vivian,Durig Thomas,Repka Michael A.

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics

Reference49 articles.

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2. Narang AS, Rao VM, Desai DS. Effect of antioxidants and silicates on peroxides in povidone. JPharmSci Elsevier. 2012;101:127–39.

3. Guideline IHT. Q3B (R2) Impurities in new drug products (2006). The international conference on harmonisation of technical requirements for registration of pharmaceuticals for human use (ICH).

4. Hovorka SW, Schöneich C. Oxidative degradation of pharmaceuticals: theory, mechanisms and inhibition. J Pharm Sci. 2001;90:253–69.

5. Tallon MA, Malawer EG, Machnicki NI, Brush PJ, Wu CS, Cullen JP. The effect of crosslinker structure upon the rate of hydroperoxide formation in dried, crosslinked poly (vinylpyrrolidone). Journal of applied polymer science. Wiley Online Library. 2008;107:2776–85.

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