Relative Precision of Inhaler Aerodynamic Particle Size Distribution (APSD) Metrics by Full Resolution and Abbreviated Andersen Cascade Impactors (ACIs): Part 1

Author:

Mitchell Jolyon P.,Nagel Mark W.,Doyle Cathy C.,Ali Rubina S.,Avvakoumova Valentina I.,Christopher J. David,Quiroz Jorge,Strickland Helen,Tougas Terrence,Lyapustina Svetlana

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics

Reference14 articles.

1. Mitchell JP, Nagel MW. Cascade impactors for the size characterization of aerosols from medical inhalers: their uses and limitations. J Aerosol Med. 2003;16:341–77.

2. Bonam M, Christopher D, Cipolla D, Donovan B, Goodwin D, Holmes S, et al. Minimizing variability of cascade impaction measurements in inhalers and nebulizers. AAPS PharmSciTech. 2008;9(2):404–13.

3. Van Oort M, Roberts W. Variable flow-variable stage-variable volume strategy for cascade impaction testing of inhalation aerosols. In: Dalby RN, Byron PR, Farr SJ, editors. Respiratory drug delivery—V. Buffalo Grove: Interpharm Press Inc; 1996. p. 418–21.

4. Christopher D, Curry P, Doub B, Furnkranz K, Lavery M, Lin K, et al. Considerations for the development and practice of cascade impaction testing including a mass balance failure investigation tree. J Aerosol Med. 2003;16:235–47.

5. Mitchell JP. The role of aerosol measurement for aerodynamic particle size distribution (APSD) in a quality-by-design (QbD) environment. In: Dalby RN, Byron PR, Peart J, Suman JD, Farr SJ, Young PM, editors. Respiratory drug delivery 2008. River Grove: Davis Healthcare International Publishing LLC; 2008. p. 779–83.

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