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Design of a Personalized Nasal Device (Matrix-Piston Nasal Device, MPD) for Drug Delivery: a 3D-Printing Application

  • Published:2022-07-28 Issue:6 Volume:23 Page:
  • ISSN:1530-9932
  • Container-title:AAPS PharmSciTech
  • language:en
  • Short-container-title:AAPS PharmSciTech

Author:

Menegatou Ioanna-Maria,Papakyriakopoulou Paraskevi,Rekkas Dimitrios M.,Dallas Paraskevas,Valsami Georgia

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics

Reference43 articles.

1. Spencer DC, Sinha SR, Choi EJ, Cleveland JM, King A, Meng TC, Pullman WE, Sequeira DJ, Van Ess PJ, Wheless JW. Safety and efficacy of midazolam nasal spray for the treatment of intermittent bouts of increased seizure activity in the epilepsy monitoring unit: a double-blind, randomized, placebo-controlled trial. Epilepsia. 2020;61(11):2415–25. https://doi.org/10.1111/epi.16704.

2. Segal EB, Tarquinio D, Miller I, Wheless JW, Dlugos D, Biton V, Cascino GD, Desai J, Hogan RE, Liow K, Sperling MR, Vazquez B, Cook DF, Rabinowicz AL, Carrazana E; DIAZ.001.05 Study Group. Evaluation of diazepam nasal spray in patients with epilepsy concomitantly using maintenance benzodiazepines: an interim subgroup analysis from a phase 3, long-term, open-label safety study. Epilepsia. 2021 ;62(6):1442–1450. https://doi.org/10.1111/epi.16901

3. Fedgchin M, Trivedi M, Daly EJ, Melkote R, Lane R, Lim P, Vitagliano D, Blier P, Fava M, Liebowitz M, Ravindran A, Gaillard R, Ameele HVD, Preskorn S, Manji H, Hough D, Drevets WC, Singh JB. Efficacy and safety of fixed-dose esketamine nasal spray combined with a new oral antidepressant in treatment-resistant depression: results of a randomized, double-blind, active-controlled study (TRANSFORM-1). Int J Neuropsychopharmacol. 2019;22(10):616–30. https://doi.org/10.1093/ijnp/pyz039.

4. Tepper SJ, Johnstone MR. Breath-powered sumatriptan dry nasal powder: an intranasal medication delivery system for acute treatment of migraine. Med Devices: Evid Res. 2018;11:147–56. https://doi.org/10.2147/MDER.S130900.

5. Ryan R, Elkind A, Baker CC, Mullican W, DeBussey S, Asgharnejad M. Sumatriptan nasal spray for the acute treatment of migraine. Results of two clinical studies Neurology. 1997;49(5):1225–30. https://doi.org/10.1212/wnl.49.5.1225.

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