Photodegradation of Fleroxacin Injection: II. Kinetics and Toxicological Evaluation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics
Link
http://link.springer.com/content/pdf/10.1208/s12249-013-9942-4.pdf
Reference25 articles.
1. Djurdjevic P, Laban A, Jelikic-Stankov M. Validation of an HPLC method for the determination of fleroxacin and its photo-degradation products in pharmaceutical forms. Ann Chim. 2004;94:71–83.
2. Cullmann W, Geddes AM, Weidekamm E, Urwyler H, Braunsteiner A. Fleroxacin: a review of its chemistry, microbiology, toxicology, pharmacokinetics, clinical efficacy and safety. Int J Antimicrob Agents. 1993;2:203–30.
3. Tiefenbacher EM, Haen E, Przybilla B, Kurz H. Photodegradation of some quinolones used as antimicrobial therapeutics. J Pharm Sci. 1994;83:463–7.
4. Albini A, Monti S. Photophysics and photochemistry of fluoroquinolones. Chem Soc Rev. 2003;32:238–50.
5. Martinez LJ, Li G, Chignell CF. Photogeneration of fluoride by the fluoroquinolone antimicrobials agents lomefloxacin and fleroxacin. Photochem Photobiol. 1997;65:599–602.
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