QbD-Guided Traditional Chinese Medicine Manufacturing Process: Development and Optimization of Fluid-Bed Granulation and Drying Processes for Xiaochaihu Capsules

Author:

Teng Kaixuan,Fu Hao,Wu Gelin,Gong Ping,Xie Yongjian,Zhou Peng,Gong Xingchu,Qu HaibinORCID

Funder

the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics

Reference52 articles.

1. The Chinese Pharmacopoeia. Commission CP, editor. Beijing, China: China Medical Science Press; 2020. 604 p.

2. Zheng C. The effects of the Xiaochaihu capsule on immunoglobulin A nephropathy. Clin J Chin Med. 2020;12(26):63–4.

3. Wu L, Geng B, Zhang R, Yong D, Xu J. Study on antibacterial and liver protective effects of Xiaochaihu capsule. Pharmacol Clin Chin Materia Med. 1999;06:3–5.

4. Zhang Y, Zhou X, Shao Q, Ze F, Wang S. Anti-inflammatory effect of Xiaochaihutang in rats with collagen-induced arthritis and the mechanism. Immunol J. 2015;31(09):781–5.

5. Liu J, Sun R. Protective effect of Xiaochaihu decoction on non-alcoholic steatohepatitis model mice. Chin Tradit Herb Drugs. 2020;51(14):3708–16.

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