Insights into the Role of Compendial/Biorelevant Media on the Supersaturation Behaviour of Drug Combination (Drug-Drug Interaction) and Precipitation Inhibition by Polymers
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics
Link
https://link.springer.com/content/pdf/10.1208/s12249-022-02448-w.pdf
Reference35 articles.
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2. Guan J, Liu Q, Jin L, Xu H, Wu H, Zhang X, et al. Synergistic effect of Soluplus and hyaluronic acid on the supersaturation maintenance of lovastatin: the facilitated in vitro-in vivo performance and improved physical stability. Carbohydr Polym. 2019;222:114978. https://doi.org/10.1016/j.carbpol.2019.114978.
3. Figueirêdo CBM, Nadvorny D, de Medeiros Vieira ACQ, de Medeiros Schver GCR, Sobrinho JLS, Neto PJR, et al. Enhanced delivery of fixed-dose combination of synergistic antichagasic agents posaconazole-benznidazole based on amorphous solid dispersions. Eur J Pharm Sci. 2018;119:208–18. https://doi.org/10.1016/j.ejps.2018.04.024 (Elsevier).
4. Arca HÇ, Mosquera-Giraldo LI, Dahal D, Taylor LS, Edgar KJ. Multidrug, anti-HIV amorphous solid dispersions: nature and mechanisms of impacts of drugs on each other’s solution concentrations. Mol Pharmaceutics. 2017;14:3617–27. https://doi.org/10.1021/acs.molpharmaceut.7b00203.
5. Trasi NS, Taylor LS. Thermodynamics of highly supersaturated aqueous solutions of poorly water-soluble drugs-impact of a second drug on the solution phase behavior and implications for combination products. J Pharm Sci. 2015;104:2583–93. https://doi.org/10.1002/jps.24528.
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