Development and Evaluation of Amorphous Solid Dispersion of Riluzole with PBPK Model to Simulate the Pharmacokinetic Profile
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmaceutical Science,Agronomy and Crop Science,Ecology,Aquatic Science,General Medicine,Ecology, Evolution, Behavior and Systematics
Link
https://link.springer.com/content/pdf/10.1208/s12249-023-02680-y.pdf
Reference55 articles.
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2. Bhujbal SV, Mitra B, Jain U, Gong Y, Agrawal A, Karki S, Taylor LS, Kumar S, Zhou QT. Pharmaceutical amorphous solid dispersion: a review of manufacturing strategies. Acta Pharm Sin B. 2021;11(8):2505–36. https://doi.org/10.1016/j.apsb.2021.05.014.
3. Dhondale MR, Thakor P, Nambiar AG, Singh M, Agrawal AK, Shastri NR, Kumar D. Co-Crystallization approach to enhance the stability of moisture-sensitive drugs. Pharmaceutics. 2023;15(1):189. https://doi.org/10.3390/pharmaceutics15010189.
4. Dash RP, Babu RJ, Srinivas NR. Two decades-long journey from riluzole to edaravone: revisiting the clinical pharmacokinetics of the only two amyotrophic lateral sclerosis therapeutics. Clin Pharmacokinet. 2018;57:1385–98. https://doi.org/10.1007/s40262-018-0655-4.
5. Doble A. The pharmacology and mechanism of action of riluzole. Neurology. 1996;47(6 Suppl 4):233S-S241. https://doi.org/10.1212/WNL.47.6_Suppl_4.233S.
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