Mycobacterium tuberculosis–specific CD8+T Cells Preferentially Recognize Heavily Infected Cells

Author:

Lewinsohn Deborah A.,Heinzel Amy S.,Gardner James M.,Zhu Liqing,Alderson Mark R.,Lewinsohn David M.

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Reference53 articles.

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2. Muller I, Cobbold SP, Waldmann H, Kaufmann SH. Impaired resistance toMycobacterium tuberculosisinfection after selectivein vivodepletion of L3T4+and Lyt-2+T cells.Infect Immun1987;55:2037–2041.

3. Flory CM, Hubbard RD, Collins FM. Effects ofin vivoT lymphocyte subset depletion on mycobacterial infections in mice.J Leukoc Biol1992;51:225–229.

4. Leveton C, Barnass S, Champion B, Lucas S, De Souza B, Nicol M, Banerjee D, Rook G. T-cell-mediated protection of mice against virulentMycobacterium tuberculosis.Infect Immun1989;57:390–395.

5. Caruso AM, Serbina N, Klein E, Triebold K, Bloom BR, Flynn JL. Mice deficient in CD4 T cells have only transiently diminished levels of IFN-γ, yet succumb to tuberculosis.J Immunol1999;162:5407–5416.

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