Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial

Author:

Slebos Dirk-Jan1,Shah Pallav L.2ORCID,Herth Felix J. F.34,Pison Christophe5,Schumann Christian6,Hübner Ralf-Harto7,Bonta Peter I.8,Kessler Romain9,Gesierich Wolfgang10,Darwiche Kaid11ORCID,Lamprecht Bernd12,Perez Thierry13,Skowasch Dirk14,Deslee Gaetan15,Marceau Armelle16,Sciurba Frank C.17,Gosens Reinoud18,Hartman Jorine E.1,Srikanthan Karthi2,Duller Marina19,Valipour Arschang19,Valipour Arschang,Abele Christine,Firlinger Irene,Kothakuzhakal Kiran,Duller Marina,Lamprecht Bernd,Kropfmueller Roland,Holzmann Kornelia,Rathmeier Sandra,Hubner Ralf,Erdmann Leonore,Temmesfeld-Wollbrück Bettina,Glösenkamp Christoph Ruwwe,Gesierich Wolfgang,Reichenberger Frank,Niehaus Christa,Herth Felix,Eberhardt Ralf,Gompelmann Daniela,Rump Brigitte,Darwiche Kaid,Eisenmann Stephan,Kaiser Ulrike,Schwarz Birte,Sampel Ulrike,Schumann Christian,Kaiser Robert,Schumann-Stoiber Kathryn,Skowasch Dirk,Ring Sabine,Pison Christophe,Briault Amandine,Arbib Francois,Jondot Marie,Perez Thierry,Fournier Clement,Matran Regis,Catto Michele,Bautin Nathalie,De Broucker Virginie,Willemin Marie,Prevotat Anne,Wemeau Ludivine,Gicquello Alice,Foulon Morgane,Camara Hasna,Deslee Gaetan,Vallerand Herve,Dury Sandra,Gras Delphine,Bonnaire-Verdier Margaux,Kessler Romain,Hirschi Sandrine,Porzio Michele,Degot Tristan,Canuet Mathieu,Schuller Armelle,Stauder Julien,Azouaou Sahra Ali,Marceau Armelle,Mal Hervé,Costa Yolande,Shah Pallav L.,Garner Justin,Srikanthan Karthi,Caneja Cielito,Thornton John,Slebos Dirk-Jan,Ten Hacken Nick,Hartman Jorine,Klooster Karin,Augustijn Sonja,Bonta Peter,Annema Jouke,van de Pol Marianne,Goorsenberg Annika

Affiliation:

1. Department of Pulmonary Diseases and

2. Royal Brompton & Harefield NHS Trust, Chelsea & Westminster Hospital and Imperial College London, London, United Kingdom

3. Department of Pneumology and Critical Care Medicine, Thoraxklinik, and

4. Translational Lung Research Center Heidelberg, University of Heidelberg, Heidelberg, Germany

5. CHU Grenoble Alpes, Service Universitaire Pneumologie Physiologie, Université Grenoble Alpes, Grenoble, France

6. Clinic of Pneumology, Thoracic Oncology, Sleep and Respiratory Critical Care, Klinikverbund Kempten-Oberallgäu, Kempten and Immenstadt, Germany

7. Charité Universitätsmedizin Berlin, Medizinische Klinik m. Schw. Infektiologie und Pneumologie, Campus Virchow, Berlin, Germany

8. Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands

9. Service de Pneumologie, Nouvel Hôpital Civil, Université de Strasbourg, Strasbourg, France

10. Asklepios-Fachkliniken Munich-Gauting, Comprehensive Pneumology Center Munich, Gauting, Germany

11. Department of Pulmonary Medicine, Section of Interventional Pneumology, Ruhrlandklinik–University Hospital Essen, University of Duisburg-Essen, Essen, Germany

12. Department of Pulmonary Medicine, Kepler Universitatsklinikum GmbH, Linz, Austria

13. CHU de Lille–Hôpital Calmette, Lille, France

14. Department of Internal Medicine II–Cardiology/Pneumology, University of Bonn, Bonn, Germany

15. CHU de Reims, Hôpital Maison Blanche, Service de Pneumologie, Reims, France

16. Service de Pneumologie, Hôpital Universitaire Bichat, Paris, France

17. Department of Molecular Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

18. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and

19. Department of Respiratory and Critical Care Medicine, Karl-Landsteiner-Institute for Lung Research and Pulmonary Oncology, Krankenhaus Nord–Klinik Floridsdorf, Vienna, Austria

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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