1. Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California
2. School of Medicine, Johns Hopkins University, Baltimore, Maryland
3. St. George’s, University of London, London, United Kingdom
4. Department of Medicine, University of Texas Health Science Center, San Antonio, Texas
5. South Texas Veterans Administration Medical Center, San Antonio, Texas; and
6. Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa