1. The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada
2. Department of Medicine, The University of Toronto, Toronto, Ontario, Canada
3. Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
4. Department of Medicine, McGill University, Montreal, Quebec, Canada; and
5. Centre de Recherche, Hopital Laval, Universite Laval, Quebec City, Quebec, Canada.