1. Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
2. Sunnybrook Research Institute, Toronto, Ontario, Canada
3. ICES, Toronto, Ontario, Canada
4. Interdepartmental Division of Critical Care Medicine
5. Department of Anesthesia
6. Department of Medicine, and
7. Critical Care Division, Department of Medicine, Maisonneuve-Rosemont Hospital affiliated with the University of Montreal, Montreal, Quebec, Canada; and
8. Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
9. Li Ka Shing Knowledge Institute and
10. Department of Anesthesia, St. Michael’s Hospital, Toronto, Ontario, Canada