1. Translational Medicine, The Research Institute
2. Department of Critical Care Medicine
3. Department of Anesthesiology, and
4. Interdepartmental Division of Critical Care Medicine
5. Division of Neonatology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada
6. Department of Surgery, and
7. Department of Physiology, University of Toronto, Toronto, Canada
8. Keenan Research Centre for Biomedical Sciences, St. Michael’s Hospital, Toronto, Canada; and
9. Institute of Physiology, Charité–Universitätsmedizin, Berlin, Germany