Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis

Author:

Allen Richard J.1ORCID,Guillen-Guio Beatriz2,Oldham Justin M.3,Ma Shwu-Fan4,Dressen Amy5,Paynton Megan L.1ORCID,Kraven Luke M.1,Obeidat Ma'en6,Li Xuan6,Ng Michael7,Braybrooke Rebecca89,Molina-Molina Maria101112,Hobbs Brian D.134ORCID,Putman Rachel K.4,Sakornsakolpat Phuwanat1314ORCID,Booth Helen L.15,Fahy William A.16,Hart Simon P.17,Hill Mike R.18,Hirani Nik19,Hubbard Richard B.89,McAnulty Robin J.20,Millar Ann B.21,Navaratnam Vidyia89ORCID,Oballa Eunice16,Parfrey Helen22,Saini Gauri23ORCID,Whyte Moira K. B.19,Zhang Yingze2425,Kaminski Naftali26,Adegunsoye Ayodeji27,Strek Mary E.27,Neighbors Margaret5,Sheng Xuting R.5,Gudmundsson Gunnar2829,Gudnason Vilmundur2930,Hatabu Hiroto3132,Lederer David J.3334ORCID,Manichaikul Ani3536,Newell John D.3738,O’Connor George T.3940,Ortega Victor E.41,Xu Hanfei42,Fingerlin Tasha E.4344,Bossé Yohan45ORCID,Hao Ke4647,Joubert Philippe45,Nickle David C.48,Sin Don D.649,Timens Wim5051ORCID,Furniss Dominic7,Morris Andrew P.525354,Zondervan Krina T.5255,Hall Ian P.569ORCID,Sayers Ian569,Tobin Martin D.157,Maher Toby M.5859,Cho Michael H.134,Hunninghake Gary M.432,Schwartz David A.436061,Yaspan Brian L.5,Molyneaux Philip L.5859,Flores Carlos2621263ORCID,Noth Imre4,Jenkins R. Gisli569,Wain Louise V.157ORCID

Affiliation:

1. Department of Health Sciences, University of Leicester, Leicester, United Kingdom

2. Unidad de Investigacion, Hospital Universitario Ntra. Sra. de Candelaria and

3. Department of Internal Medicine, University of California Davis, Davis, California

4. Division of Pulmonary and Critical Care Medicine

5. Genentech, South San Francisco, California

6. The University of British Columbia Centre for Heart Lung Innovation, St. Paul’s Hospital, Vancouver, British Columbia, Canada

7. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

8. Division of Epidemiology and Public Health and

9. National Institute for Health Research, Nottingham Biomedical Research Centre and

10. Servei de Pneumologia, Laboratori de Pneumologia Experimental, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona, Spain

11. Campus de Bellvitge, Universitat de Barcelona, Barcelona, Spain

12. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain

13. Channing Division of Network Medicine

14. Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

15. Department of Thoracic Medicine, University College London Hospitals NHS Foundation Trust, London, United Kingdom

16. Discovery Medicine, GlaxoSmithKline, Stevenage, United Kingdom

17. Respiratory Research Group, Hull York Medical School, Castle Hill Hospital, Cottingham, United Kingdom

18. Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health

19. Medical Research Council Centre for Inflammation Research, The University of Edinburgh, Edinburgh, United Kingdom

20. UCL Respiratory Centre for Inflammation and Tissue Repair, University College London, London, United Kingdom

21. Academic Respiratory Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

22. Cambridge Interstitial Lung Disease Service, Royal Papworth Hospital, Cambridge, United Kingdom

23. Respiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom

24. Division of Pulmonary, Allergy and Critical Care Medicine and

25. Simmons Center for Interstitial Lung Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania

26. Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut

27. Section of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois

28. Department of Respiratory Medicine, Landspital University Hospital, Reykjavik, Iceland

29. Faculty of Medicine University of Iceland, Reykjavik, Iceland

30. Icelandic Heart Association, Kopavogur, Iceland

31. Department of Radiology, and

32. Center for Pulmonary Functional Imaging, Brigham and Women’s Hospital, Boston, Massachusetts

33. Department of Medicine, College of Physicians and Surgeons and

34. Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York

35. Center for Public Health Genomics, and

36. Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia

37. Division of Cardiovascular and Pulmonary Imaging, Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, Iowa

38. Department of Radiology, University of Washington, Seattle, Washington

39. Department of Medicine, Pulmonary Center, Boston University, Boston, Massachusetts

40. NHLBI’s Framingham Heart Study, Framingham, Massachusetts

41. Center for Precision Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina

42. Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts

43. Center for Genes, Environment and Health, National Jewish Health, Denver, Colarado

44. Department of Biostatistics and Informatics

45. Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada

46. Department of Genetics and Genomic Sciences and

47. Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York

48. Merck Research Laboratories, Genetics and Pharmacogenomics, Boston, Massachusetts

49. Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

50. University Medical Center Groningen, University of Groningen, Department of Pathology and Medical Biology and

51. Groningen Research Institute for Asthma and COPD, Groningen, the Netherlands

52. Wellcome Centre for Human Genetics, and

53. Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom

54. Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, United Kingdom

55. Oxford Endometriosis Care and Research Centre, Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, United Kingdom

56. Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom

57. National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom

58. National Institute for Health Research Respiratory Clinical Research Facility, Royal Brompton Hospital, London, United Kingdom

59. National Heart and Lung Institute, Imperial College, London, United Kingdom; and

60. Department of Medicine, and

61. Department of Immunology, University of Colorado Denver, Denver, Colorado

62. Instituto de Tecnologías Biomédicas, Universidad de La Laguna, Santa Cruz de Tenerife, Spain

63. Instituto Tecnológico y de Energías Renovables, S.A., Santa Cruz de Tenerife, Spain

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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