Randomized Controlled Trial of Urokinase versus Placebo for Nondraining Malignant Pleural Effusion

Author:

Mishra Eleanor K.1,Clive Amelia O.2,Wills Genevieve H.3,Davies Helen E.4,Stanton Andrew E.5,Al-Aloul Mohamed6,Hart-Thomas Alan7,Pepperell Justin8,Evison Matthew6,Saba Tarek9,Harrison Richard Neil10,Guhan Anur11,Callister Matthew E.12,Sathyamurthy Ramamurthy13,Rehal Sunita3,Corcoran John P.14,Hallifax Robert14,Psallidas Ioannis14,Russell Nicky14,Shaw Rachel14,Dobson Melissa14,Wrightson John M.14,West Alex15,Lee Y. C. Gary16ORCID,Nunn Andrew J.3,Miller Robert F.17,Maskell Nick A.2,Rahman Najib M.1418ORCID

Affiliation:

1. Norfolk and Norwich Pleural Unit, Norfolk and Norwich University Hospital NHS Foundation Trust, Norfolk, United Kingdom

2. Academic Respiratory Unit, School of Clinical Sciences, Southmead Hospital, University of Bristol, Bristol, United Kingdom

3. Medical Research Council Clinical Trials Unit and

4. Cardiff and Vale University Health Board, Cardiff, United Kingdom

5. Great Western Hospital, Swindon, United Kingdom

6. University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom

7. Calderdale and Huddersfield NHS Foundation Trust, Huddersfield, United Kingdom

8. Somerset Lung Centre, Musgrove Park Hospital, Taunton, United Kingdom

9. Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, United Kingdom

10. North Tees and Hartlepool Hospitals NHS Foundation Trust, North Tees, United Kingdom

11. University Hospital Ayr, Ayr, United Kingdom

12. Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

13. James Cook University Hospital, South Tees, United Kingdom

14. Oxford Respiratory Trials Unit and Oxford Pleural Diseases Unit, Churchill Hospital, Oxford, United Kingdom

15. Guy’s and St. Thomas’ NHS Foundation Trust, London, United Kingdom

16. School of Medicine and Pharmacology, University of Western Australia, Perth, Australia; and

17. Research Department of Infection and Population Health, Institute of Epidemiology and Healthcare, University College London, London, United Kingdom

18. National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Reference18 articles.

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