Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally over Time-Reference-Cited by-同舟云学术

Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally over Time

Published:2024-04-01 Issue:7 Volume:209 Page:816-828
ISSN:1073-449X
Container-title:American Journal of Respiratory and Critical Care Medicine
language:en
Short-container-title:Am J Respir Crit Care Med

Author:

Sinha Pratik¹,Neyton Lucile²^ORCID,Sarma Aartik²,Wu Nelson²,Jones Chayse²,Zhuo Hanjing²,Liu Kathleen D.²³,Sanchez Guerrero Estella⁴,Ghale Rajani²⁴,Love Christina⁴,Mick Eran⁴⁵^ORCID,Delucchi Kevin L.⁶,Langelier Charles R.⁴⁵,Thompson B. Taylor⁷,Matthay Michael A.²⁸,Calfee Carolyn S.²⁸

Affiliation:

1. Division of Clinical and Translational Research, Division of Critical Care, Department of Anesthesia, Washington University School of Medicine, St. Louis, Missouri;

2. Division of Pulmonary, Critical Care, Allergy and Sleep Medicine,

3. Division of Nephrology, and

4. Division of Infectious Diseases, Department of Medicine,

5. Chan Zuckerberg Biohub, San Francisco, California; and

6. Department of Psychiatry and Behavioral Sciences, and

7. Division of Pulmonary and Critical Care, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts

8. Department of Anesthesia, University of California, San Francisco, San Francisco, California;

Funder

National Heart, Lung, and Blood Institute Division of Intramural Research

National Institute of General Medical Sciences

Publisher

American Thoracic Society

Link

https://www.atsjournals.org/doi/pdf/10.1164/rccm.202308-1490OC

Reference31 articles.

1. Pathophysiology of the Acute Respiratory Distress Syndrome

2. Clinical trials in acute respiratory distress syndrome: challenges and opportunities

3. Phenotypes in acute respiratory distress syndrome

4. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials

5. Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

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