1. Interdepartmental Division of Critical Care Medicine and
2. Division of Respirology, Department of Medicine, University Health Network, Toronto, Ontario, Canada;
3. Department of Anesthesiology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;
4. Adult Intensive Care Unit, Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno” (CEMIC), Buenos Aires, Argentina;
5. Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
6. Toronto General Hospital Research Institute, Toronto, Ontario, Canada