1. Interdepartmental Division of Critical Care Medicine and
2. University Health Network, Toronto, Ontario, Canada;
3. St. Michael’s Hospital, Unity Health Toronto, Toronto, Ontario, Canada;
4. Critical Care Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel;
5. Department of Medicine, University of Toronto, Toronto, Ontario, Canada;
6. Li Ka Shing Knowledge Institute, Keenan Research Centre, Toronto, Ontario, Canada;
7. Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom; and
8. Kingston Health Sciences Centre, Kingston, Ontario, Canada