Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease

Author:

Lu Zhe1,Van Eeckhoutte Hannelore P.2,Liu Gang13,Nair Prema M.1,Jones Bernadette1,Gillis Caitlin M.345,Nalkurthi B. Christina3,Verhamme Fien2,Buyle-Huybrecht Tamariche2,Vandenabeele Peter45,Vanden Berghe Tom456,Brusselle Guy G.2,Horvat Jay C.1,Murphy James M.78,Wark Peter A.1ORCID,Bracke Ken R.2,Fricker Michael1,Hansbro Philip M.13ORCID

Affiliation:

1. Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia;

2. Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium;

3. Centre for Inflammation, Centenary Institute and University of Technology Sydney, Faculty of Science, School of Life Sciences, Sydney, New South Wales, Australia;

4. VIB Center for Inflammation Research, Department for Biomedical Molecular Biology, and

5. Methusalem Program: Cell Death Activity Regulation in Inflammation and Cancer, Ghent University, Ghent, Belgium;

6. Department Biomedical Sciences, University of Antwerp, Antwerp, Belgium; and

7. Walter and Eliza Hall Institute of Medical Research and

8. Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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