The Effect of a Liberal Approach to Glucose Control in Critically Ill Patients with Type 2 Diabetes: A Multicenter, Parallel-Group, Open-Label Randomized Clinical Trial

Author:

Poole Alexis P.123,Finnis Mark E.1234,Anstey James45,Bellomo Rinaldo346,Bihari Shailesh7ORCID,Biradar Vishwanath8,Doherty Sarah5,Eastwood Glenn346,Finfer Simon9,French Craig J.410,Heller Simon11,Horowitz Michael1213,Kar Palash12,Kruger Peter S.1415,Maiden Matthew J.1216ORCID,Mårtensson Johan17,McArthur Colin J.18,McGuinness Shay P.19,Secombe Paul J.320,Tobin Antony E.421,Udy Andrew A.322,Young Paul J.342324ORCID,Deane Adam M.45ORCID,Schultz Rebecca,Secombe Paul,Butler Magdalena,Cowdrey Keri-Anne,Gilder Eileen,McGuinness Shay,O’Connor Karina,Parke Rachael,Ryan Samantha,Woolett Melissa,Chen Yan,McArthur Colin,McConnochie Rachael,Newby Lynette,Simmonds Catherine,Bellomo Rinaldo,Eastwood Glenn,Peck Leah,Young Helen,Bihari Shailesh,Comerford Sharon,Jin Xia,Bates Samantha,French Craig,Marshall Fiona,McEldrew Rebecca,Morgan Rebecca,Tippett Anna,Towns Miriam,Morrison Lynette,Sutton Joanne,White Hayden,Biradar Vishwanath,Soar Natalie,Harward Meg,Kruger Peter,Mackay Josephine,Meyer Jason,Saylor Emma,Wetzig Krista,Brown Nerissa,Finnis Mark,Glasby Kathleen,O’Connor Stephanie,Poole Alex,Rivett Justine,Anstey James,Barge Deborah,Byrne Kathleen,Clancy Annabelle,Deane Adam,Driscoll Alana,Barbazza Leanne,Holmes Jennifer,Smith Roger,Tobin Anthony,Bates Samantha,French Craig,Marshall Fiona,McEldrew Rebecca,Morgan Rebecca,Tippett Anna,Towns Miriam,Board Jasmin,Martin Emma,McCracken Phoebe,Udy Andrew,Vallance Shirley,Young Meredith,Bone Allison,Horton Michelle,Maiden Matthew,Salerno Tania,Trickey Jemma,Latimer-Bell Charlie,Delaney Kirsha,Hendry Deborah,Lawrence Cassie,Lesona Eden,Milington Alexandra,Navarra Leanlove,Olatunji Shaanti,Cruz Raulle Sol,Cruz Rose Sol,Young Chelsea,Young Paul

Affiliation:

1. Discipline of Acute Care Medicine and

2. Intensive Care Unit and

3. Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia;

4. Department of Critical Care, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia;

5. Department of Intensive Care, Royal Melbourne Hospital, Parkville, Victoria, Australia;

6. Department of Intensive Care, Austin Hospital, Heidelberg, Victoria, Australia;

7. Department of Intensive and Critical Care Unit, Flinders Medical Centre, Bedford Park, South Australia, Australia;

8. Department of Intensive Care, Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia;

9. The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia;

10. Department of Intensive Care, Western Health, Footscray, Victoria, Australia;

11. Clinical Diabetes, Endocrinology, and Metabolism, University of Sheffield, Sheffield, United Kingdom;

12. Centre for Research Excellence in Translating Nutrition Science to Good Health, University of Adelaide, Adelaide, South Australia, Australia;

13. Medicine and Endocrine Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia;

14. Department of Intensive Care, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia;

15. School of Medicine, University of Queensland, Herston, Queensland, Australia;

16. Intensive Care Unit, Barwon Health, Geelong, Victoria, Australia;

17. Section of Anaesthesia and Intensive Care, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden;

18. Department of Critical Care Medicine and

19. Cardiothoracic and Vascular Intensive Care and High Dependency Unit, Auckland District Health Board, Auckland, New Zealand;

20. Department of Intensive Care, Alice Springs Hospital, Alice Springs, Northern Territory, Australia;

21. Department of Intensive Care, St. Vincent’s Hospital Melbourne, Fitzroy, Victoria, Australia;

22. Department of Intensive Care, The Alfred Hospital, Prahran, Victoria, Australia;

23. Medical Research Institute of New Zealand, Wellington, New Zealand; and

24. Intensive Care Unit, Wellington Regional Hospital, Wellington, New Zealand

Funder

Melbourne Academic Centre for Health Rapid Applied Research Translation Grant

Diabetes Australia Research Trust Project Grant

Royal Australasian College of Physicians Diabetes Australia Research Establishment Fellowship

The Royal Adelaide Hospital Research Committee Project Grant

Intensive Care Foundation Fisher and Paykel Research Project Grant

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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