Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary T-Helper Cell Type 17 Response that Mitigates Susceptibility to Streptococcus pneumoniae-Reference-Cited by-同舟云学术

Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary T-Helper Cell Type 17 Response that Mitigates Susceptibility to Streptococcus pneumoniae

Published:2021-05-01 Issue:9 Volume:203 Page:1099-1111
ISSN:1073-449X
Container-title:American Journal of Respiratory and Critical Care Medicine
language:en
Short-container-title:Am J Respir Crit Care Med

Author:

Wu Benjamin G.¹²³^ORCID,Sulaiman Imran¹²,Tsay Jun-Chieh J.¹²³,Perez Luisanny¹²,Franca Brendan¹²,Li Yonghua¹²,Wang Jing¹⁴,Gonzalez Amber N.¹²,El-Ashmawy Mariam²,Carpenito Joseph¹²,Olsen Evan¹²,Sauthoff Maya¹²,Yie Kevin¹²,Liu Xiuxiu⁵,Shen Nan⁶,Clemente Jose C.⁶,Kapoor Bianca²,Zangari Tonia⁷,Mezzano Valeria⁸⁹,Loomis Cynthia⁸¹⁰,Weiden Michael D.¹²,Koralov Sergei B.¹⁰,D’Armiento Jeanine¹¹,Ahuja Sunil K.¹²,Wu Xue-Ru¹⁰¹³,Weiser Jeffrey N.⁷,Segal Leopoldo N.¹²

Affiliation:

1. Division of Pulmonary, Critical Care and Sleep Medicine

2. Department of Medicine

3. Division of Pulmonary and Critical Care, New York Harbor Veterans Affairs, New York, New York

4. Beijing Chaoyang Hospital, Capital Medical University, Beijing, China

5. Division of Pediatrics, Longhua Hospital, Shanghai University of Chinese Medicine, Shanghai, China

6. Department of Genetics and Genomic Sciences and Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York

7. Department of Microbiology

8. Division of Cardiology, Department of Medicine and

9. Experimental Pathology Research Laboratory, Division of Advanced Research Technologies, and

10. Department of Pathology, NYU Langone Health, New York, New York

11. Department of Anesthesiology, School of Medicine, Columbia University, New York, New York; and

12. University of Texas Health Science Center, San Antonio, Texas

13. Department of Urology, School of Medicine, New York University, New York, New York

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

Reference51 articles.

1. Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

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5. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

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