Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis

Author:

Mulenga Humphrey1,Musvosvi Munyaradzi1,Mendelsohn Simon C.1ORCID,Penn-Nicholson Adam1,Kimbung Mbandi Stanley1,Fiore-Gartland Andrew2ORCID,Tameris Michèle1,Mabwe Simbarashe1,Africa Hadn1,Bilek Nicole1,Kafaar Fazlin1,Khader Shabaana A.3,Carstens Balie1,Hadley Katie1,Hikuam Chris1,Erasmus Mzwandile1,Jaxa Lungisa1,Raphela Rodney1,Nombida Onke1,Kaskar Masooda1,Nicol Mark P.45,Mbhele Slindile4,Van Heerden Judi4,Innes Craig6,Brumskine William6,Hiemstra Andriëtte7,Malherbe Stephanus T.7,Hassan-Moosa Razia89,Walzl Gerhard7,Naidoo Kogieleum89,Churchyard Gavin610,Hatherill Mark1ORCID,Scriba Thomas J.1ORCID,

Affiliation:

1. South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, and

2. Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington;

3. Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri;

4. Division of Medical Microbiology, Department of Pathology, University of Cape Town, Cape Town, South Africa;

5. Division of Infection and Immunity, School of Biomedical Sciences, University of Western Australia, Perth, Australia;

6. The Aurum Institute, Johannesburg, Guateng, South Africa;

7. Department of Science and Technology/National Research Foundation Centre of Excellence for Biomedical TB Research and SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa;

8. Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa;

9. Medical Research Council-CAPRISA HIV-Tuberculosis Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa; and

10. School of Public Health, University of Witwatersrand, Johannesburg, South Africa

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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