Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia–Reperfusion Injury

Author:

Akimova Tatiana12ORCID,Zhang Tianyi12,Christensen Lanette M.12,Wang Zhonglin3,Han Rongxiang12,Negorev Dmitry12,Samanta Arabinda12,Sasson Isaac E.45,Gaddapara Trivikram6,Jiao Jing7,Wang Liqing12,Bhatti Tricia R.12,Levine Matthew H.3,Diamond Joshua M.8,Beier Ulf H.7,Simmons Rebecca A.6,Cantu Edward9,Wilkes David S.1011,Lederer David J.12,Anderson Michaela12ORCID,Christie Jason D.98ORCID,Hancock Wayne W.12ORCID

Affiliation:

1. Division of Transplant Immunology, Department of Pathology and Laboratory Medicine

2. Biesecker Center for Pediatric Liver Diseases, and

3. Division of Transplant Surgery and

4. Department of Obstetrics and Gynecology, and

5. Division of Neonatology, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania;

6. Department of Pediatrics, Children’s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania;

7. Division of Nephrology

8. Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania;

9. Division of Cardiovascular Surgery, Department of Surgery

10. Division of Pulmonary, Allergy, Critical Care, and Occupational Medicine, School of Medicine, and

11. Health Lung Transplant Program, Indiana University, Indianapolis, Indiana; and

12. Division of Pulmonary, Allergy, and Critical Care Medicine, College of Physicians and Surgeons, Columbia University, New York, New York

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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