Anti-Granulocyte–Macrophage Colony–Stimulating Factor Monoclonal Antibody Gimsilumab for COVID-19 Pneumonia: A Randomized, Double-Blind, Placebo-controlled Trial

Author:

Criner Gerard J.1,Lang Frederick M.234ORCID,Gottlieb Robert L.567ORCID,Mathews Kusum S.8,Wang Tisha S.9,Rice Todd W.10,Madduri Deepu8,Bellam Shashi11,Jeanfreau Robert12,Case Amy H.13,Glassberg Marilyn K.14,Lyon George Marshall15,Ahmad Kareem16,Mendelson Robert17,DiMaio J. Michael6,Tran MaryAnn P.18,Spak Cedric W.519,Abbasi Jamil A.20,Davis Steven G.21,Ghamande Shekhar22,Shen Steven2323,Sherman Lisa23,Lowry Simon23

Affiliation:

1. Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania;

2. Roivant Sciences, New York, New York;

3. Kinevant Sciences, a wholly-owned subsidiary of Roivant Sciences, New York, New York;

4. Columbia University Vagelos College of Physicians and Surgeons, New York, New York;

5. Baylor University Medical Center, Dallas, Texas;

6. Baylor Scott & White The Heart Hospital–Plano, Plano, Texas;

7. Baylor Scott & White Heart and Vascular Hospital, Dallas, Texas;

8. Icahn School of Medicine at Mount Sinai, New York, New York;

9. University of California Los Angeles David Geffen School of Medicine, Los Angeles, California;

10. Vanderbilt University Medical Center, Nashville, Tennessee;

11. NorthShore University HealthSystem, Evanston, Illinois;

12. East Jefferson General Hospital, Metaire, Lousiana;

13. Piedmont Healthcare, Atlanta, Georgia;

14. University of Arizona College of Medicine/Banner University Medical Center, Phoenix, Arizona;

15. Emory University School of Medicine, Atlanta, Georgia;

16. Inova Fairfax Hospital, Falls Church, Virginia;

17. Jamaica Hospital Medical Center, Jamaica, New York;

18. Baylor Scott & White Medical Center–Round Rock, Round Rock, Texas;

19. Texas Centers for Infectious Disease Associates, Dallas, Texas;

20. Baylor Scott & White All Saints Medical Center, Fort Worth, Texas;

21. Baylor Scott & White Medical Center–Irving, Irving, Texas;

22. Baylor Scott & White Medical Center–Temple, Temple, Texas; and

23. Sumitovant Biopharma, New York, New York

Funder

Kinevant Sciences

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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