Biological Subphenotypes of Acute Respiratory Distress Syndrome Show Prognostic Enrichment in Mechanically Ventilated Patients without Acute Respiratory Distress Syndrome

Author:

Heijnen Nanon F. L.1ORCID,Hagens Laura A.2ORCID,Smit Marry R.2ORCID,Cremer Olaf L.3,Ong David S. Y.45,van der Poll Tom67,van Vught Lonneke A.2,Scicluna Brendon P.68,Schnabel Ronny M.1,van der Horst Iwan C. C.1,Schultz Marcus J.291011,Bergmans Dennis C. J. J.1,Bos Lieuwe D. J.212ORCID,de Beer Friso M.,Bos Lieuwe D.,Glas Gerie J.,Horn Janneke,Hoogendijk Arie J.,van Hooijdonk Roosmarijn T.,Huson Mischa A.,van der Poll Tom,Scicluna Brendon,Schouten Laura R.,Schultz Marcus J.,Straat Marleen,van Vught Lonneke A.,Wieske Luuk,Wievel Maryse A.,Witteveen Esther,Bonten Marc J.,Cremer Olaf L.,Frencken Jos F.,van de Groep Kirsten,Klein Klouwenberg Peter M.,Koster-Brouwer Maria E.,Ong David S.,Varkila Meri R.,Verboom Diana M.

Affiliation:

1. Department of Intensive Care Medicine, Maastricht University Medical Center+, Maastricht, the Netherlands;

2. Department of Intensive Care Medicine,

3. Center for Experimental and Molecular Medicine,

4. Division of Infectious Diseases,

5. Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Infection and Immunity,

6. Laboratory of Experimental Intensive Care and Anesthesiology, and

7. Department of Respiratory Medicine, Amsterdam University Medical Centers, location Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands;

8. Department of Intensive Care Medicine and

9. Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands;

10. Department of Medical Microbiology and Infection Control, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands;

11. Mahidol–Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; and

12. Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Publisher

American Thoracic Society

Subject

Critical Care and Intensive Care Medicine,Pulmonary and Respiratory Medicine

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